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New Obesity Vaccine? Possible

Posted: August 23rd, 2012 | Author: | Filed under: Passport Health Sarasota-Bradenton Announcements | Tags: , , , , | Comments Off on New Obesity Vaccine? Possible
What scientists call "Overweight" ch...

What scientists call “Overweight” changes with our knowledge of human health (Photo credit: Wikipedia)

Researchers at Braasch Biotech seeking an obesity vaccine for humans achieved promising results in a study using mice. They found that chubby mice quickly shed 10% of their body weight when injected with modified somatostatin, a peptide hormone.

The scientists fattened up the mice over the course of 8 weeks and right through the 6-week study. The mice received a dose of the vaccines–two somatostatin vaccinations, JH17 and JH18–at the beginning of the study and on day 22. The vaccines lead to production of antibodies to somatostatin–a hormone peptide that blocks activity of growth hormone and insulin-like growth factor (IGF-1)–in order to boost energy use and burn fat. Four days after the first vaccine injections, the overweight mice dropped 10% of their body weight without negative effects on growth hormone, IGF-1 or insulin levels, according to a release.

“This study demonstrates the possibility of treating obesity with vaccination,” said Keith Haffer, a scientist at Braasch Biotech, in a statement. “Although further studies are necessary to discover the long-term implications of these vaccines, treatment of human obesity with vaccination would provide physicians with a drug- and surgical-free option against the weight epidemic.”

A juggernaut of hype will surely follow the release of a vaccine to combat obesity, a common cause for heart disease and Type 2 diabetes, but animal testing only preludes the years of human clinical trials ahead.


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